Genomics & Health Informatics

The mass generation of high-content genomic, imaging and digital data has brought rapid advances in our understanding of cell biology and human diseases, and offers promising avenues for the field of precision medicine. A major obstacle revolves around delivering meaningful information from these data, requiring the deployment of a variety of methods such as statistics, machine learning and data visualization in tight collaboration with clinicians.

The Genomics & Health Informatics Group was created in 2019 to develop statistical and machine-learning methods to integrate genomic, clinical, and imaging data. The group aims to accelerate the diagnosis and improve the understanding and treatment of complex diseases such as neuro-degenerative disorders in collaboration with clinical neuroscientists. The group has expertise in genomics, bioinformatics, RNA biology, neuroscience, data science, and data visualization.

The current lines of research include:

1) the integration of longitudinal cellular imaging with genomic data to study how molecular biology shapes cellular morphology in neuro-degenerative diseases;

2) the development of machine learning methods to integrate longitudinal digital data with genomics to study how individual differences in motor and cognitive behaviors emerge and how such differences may confer vulnerability to neurodegenerative diseases.

In collaborating with clinicians and expert laboratories in molecular neuroscience and bioengineering, the group has access to unique high quality data including longitudinal RNA-sequencing (Patani laboratory, Francis Crick Institute, London) and time-lapse cellular imaging (Serio lab, Kings College, London) from motor neuron cultures obtained from healthy and sick donors.

 

Group News

GHI first summer walk
institute — last modified Sep 21, 2022

In July the GHI group went for his first summer walk at the Dorbon’s alpage above the stunning village of Derborence.

The Swiss Institute of Bioinformatics and Idiap start a partnership
institute — Sep 13, 2022

Bringing artificial intelligence and bioinformatics closer in Switzerland, Idiap and the Swiss Institute of Bioinformatics (SIB) signed a collaboration agreement. By becoming a partner institution of SIB, Idiap ensures its groups active in bioinformatics benefit from SIB’s national network of expertise, while enabling the SIB to access its 30 years of experience in AI research.

L'Idiap croit en la force des femmes en science
education — last modified Feb 08, 2022

A l'occasion de la Journée Internationale des Femmes et les Filles en Sciences, venez prendre part à l'évènement virtuel Potenti'Elles, une table ronde ouverte à toutes et tous qui réunira des femmes inspirantes.

Group Job Openings

Our group is regularly posting job openings ranging from internships to researcher positions. To check the opportunities currently available or to submit a speculative applications use the link below.Our group is regularly posting job openings ranging from internships to researcher positions. To check the opportunities currently available or to submit a speculative applications use the link below.

Current Group Members

The group is led by Raphaëlle Luisier.

LUISIER, Raphaëlle
(Research Scientist)
- website


MESSORI, Elisa
(Research Assistant)
- website


DÉLITROZ, Maxime
(Research Assistant)
- website


SCHNEUWLY, Christelle
(Research Intern)
- website


KOEHN, Edouard Erwan
(Research Intern)
- website


FOURNIER, Lisa
(Master Student)
- website


Alumni